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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '539ba175b1233bdd9f6e1a962724946a4d0f5900c59709ac0064b4f2788ea0c1' 
  AND token = 'gA65TF9KOBPT4maTf3qV+NM+wCN+2PNtqVtCUQ79/ZA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}