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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '548b3c2675cd45b3dd1d91f9a858cca5c46ca2b01de720362cf6c237c92de2da' 
  AND token = 'KZNlOZ5dxh0Y7ChdYCv+5bkypp9lUFhxjdqQp0lQT0M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}