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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd2421fa8d5b7d5bfc15e4edb11078546abab28c71e08153d2c2a09c27f008fe4' 
  AND token = 'K9kRzcyn07EdpyHUu32ocnAUJ2o2V3vBG0x8jqcnAbw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}