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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '00c48cfd3241b191a82279050b398faddb91b6b78656e7ce4ad8c23295a659dd' 
  AND token = 'pOIOsyliu3e/aFCXz1O94q+cxjvwxdQYY5LRJNp446Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}