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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '20e3b2b366fa18764e72661dadbbf46ac074adbdbda129836bf5b20d2602f845' 
  AND token = 'VM5kFXyNC9Ms9OVmAD9JlQrNh0mZUaNQWcnaLaN4wiY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}