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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de496065a9c5fea64b505aa55ce8aa90d9c7bc75a70c0243b642aad811a56fdf' 
  AND token = 'PXtW50h/EWZlTJeuy14jGmAcolZb56iZEeh/qxF9uwg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}