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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c373afce088b5754e3d761b076f478d8cd9be97b8175ed5afe877d5b9ad8539' 
  AND token = '2wMxiB5SUNuEVwT9Us8BAakFbvHZL3pBV0KsqTnRjm8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}