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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '77ccb377d2461997be81c8bde93bb4b83540d48b9767d5f5bacb3e3026bdf1f1' 
  AND token = 'A9L/usjbpMIddx3zus4yLNCQiVVcFYgtC0qPIybjZg8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}