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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'df36318c19decd95022d63ac3aa6e87c645256568b79cc87a54f9e3ed84040f0' 
  AND token = 'hG4R/7E6e7Cc4liEsqQ695Cfgx95/zUOvvcZ0iIagRY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}