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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '877468f1575b16163c8cf304991e4f2374aa299beb58427f375b7e4e626b45ee' 
  AND token = 'eCokyCE3ZHU5mpN24Nwj38GHkFqybldGYFdcwbxGeBM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}