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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7fc169027b8ad8e4e9abe16d7210635c3c4681b007abb71a62828905814dd615' 
  AND token = '67wtN/We7fhg36eMRyAG7WgwwlfL0i4FsVgpyN3q2cQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}