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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '123a73a0aaf20607114579d7130bf4f5b9face9808604186fa54a95fcb266f23' 
  AND token = '8jFtI/f4e5h3brdPAy9E3rYIoO6yKeeBSHaKfCWxU6w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}