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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c2f77ded04eff821851a6d13a38d5dba45a4a8b6df691643ec33e51916360e5' 
  AND token = 'jZnZUKJvOc5blI8BlkSq35eA9AxF9so/iA/APfUlkSc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}