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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '20f4ab8394fa6cf71af71d51937f0329c53df227536db948aa5ebef6731344cb' 
  AND token = 'FHZsUHzq51h+UkEd6++E8OavKCxE14ugTbbtRALR12E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}