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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c7914fe10c2b66264f862174ee64af3dffd9642b1f7337cc74baefdb760a433' 
  AND token = 's9MOHHeje81BoN80FDX9BGTysFUttMlE4qjLZzvhMf0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}