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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6ace4efccdd3047d4f6b62d48d39907e5ed91219a2650f02e018445bf430197f' 
  AND token = 'yYT1KzJKmZVHfDh2TdLPTvPo16NTDGMj1dB0w9Usw9k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}