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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '08570a0aa8a430680d462281424d1c8d534e74651765f09b03d5b61a0ed68746' 
  AND token = 'c3Z3yg3ctOAkzUbYag+w17JMT2HHTZuM19605QQptNg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}