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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5164b09dee6f3494432555f9ce152569108595aa486cbd0e0236e5cf9d26157e' 
  AND token = 'KDKR4hyS6VaLfxQCi4FhcwIs+SXI7GwKF53AK8rZa3c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}