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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b900a321e8928fcf4e854cb91c6d155bd04ae7bed5a1f92b39ffdad21386b959' 
  AND token = 'W6CvoOWJljI/vvrM9Ke2aqEOMaWB5eTUtZhKdqKdij8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}