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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a5fb29a7776dbffddd1d3a29540d75fd5ec168db8f89926b205bf3af0f3f625f' 
  AND token = '1sk7tcvinadQ2xb65pF8GPbF5M6UBSsuwfLtx80kb4w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}