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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e80e2510d734e00ef2d55082e5d5110e1546d116744b5b7e5b6b75d29781fb2e' 
  AND token = 'Df7gDWeVir4cfMYA6BQ4NvzyGPzsZxHYKWyz3gZyZ8o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}