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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bd0287048c9df82a68aa6defff2216515b0521c85aa8fde8882cfc987fe8e6e4' 
  AND token = 'IKUMFTAcEncNg1z+etJQKXE7eeZ5RzzW78nBjNBq/F0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}