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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78757732e9b0903a27b3767e22413d25ada15dda423bc30f305d161b89cd73e1' 
  AND token = 'm0e+qqbXN+tydraAGoUWtvZkN4odAfHvQnvO3E98M4s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}