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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'edc4ee9b6e5b9a7c9a8ec5b713f3cefe34d32e5675180bb6bf355db551056b27' 
  AND token = 'CE2xHsfyxsP0c0jtgIyTkZRiUEBFJHFGCwVdjsnsg+o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}