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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c03419ef52e3a3e5a69f6cca2a2a61939a69474d9cc14c91f48669c65c800f7' 
  AND token = 'JW4mt++1Hdvt0mRSwfDTL3Sep3iXKgMWQnS2l8gI6WI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}