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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f9c710c1729bbee80a65ab27e2259fb7126a072ef5ac6fc4642e46cbcdd4b04' 
  AND token = 'GV58skF+6iHOTYLANjSskZGmjGx3846v7SXjzEprINA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}