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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fec5ccd1902009630b9fe3f4a2625d6d13874f1fead2ba86980e2cddb8800338' 
  AND token = 'FQHR0eEFil2WhYS07shtaRTW9rshUaEDPR4JSyNM/JI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}