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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b91d13889e1ce5bfd78285d72d305c72446a62c95780baadd2827b4c045e52f' 
  AND token = 'aTX6FZmOSJZKZORjr+bMQDDpyo/IAXeISu7DhY9IG04=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}