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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '385cfa4c5986b211fa377d6ba29260028f2a2dddfe0ba16f49a9e3dbb5f2222c' 
  AND token = 'c4p0NuJu9F4MnF9SvLu+ftbLkHTXqAF0hvsxEovOjdI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}