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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b0e1f05101062b90f709fbabf7f494e90a8e6b36b1ba5e66f096cd8b6d7efecb' 
  AND token = 'f0SnRJTaIOzLLlexekxPtAcmw+E4ShTBD8+dD/TzsfQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}