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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dd5c7cce526761a293f9d48d8b0e7b94357c14776622b2cee914f4b8abd129c1' 
  AND token = '7W9pS8kw+1JdTVSNmpDyswTVfsttHWEUhIjXb6RtAJA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}