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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a53831471a80a2be93c0c20cdf77ab44fa6c40be9430786094d5b91791dc3faf' 
  AND token = 'pJ1KwPs6XIv2F6q44H4OVd4Eg8iZqSmZuTUV4KVYoic=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}