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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '68ee6ab3c598dc29848c095853455073412b11526ff18d8da156be7475d71586' 
  AND token = '4IACScj3aUUeODA0N9Wpq80h4gzHcCU2D/xMmAKHG2A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}