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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f2a5cc8535a0a1ff5041ab0c87526a68b04376d29f4c2f66bd2d5d79d19c98e' 
  AND token = 'FU1TBDqgVA9oj7wiT+PqbVe5IKyz0gD5KcEvAFdbgS4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}