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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd51a2f9025aead47c2e1ef96eb38c0525f132dea359a816c748795667f2a895e' 
  AND token = 'HFTFJE+f0kU1uMigFQ3p+KR3aFgfSgHQ17jLyyMD4aI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}