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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '68523d94f981b923738fed7335c7afcfe8ba68d3cdecbcb5ae3186e31ff2f802' 
  AND token = '4h6dR1DZm9fkO/j8tuLIORTBkHomvckCaw5Y6CXTeD0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}