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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '73611d8fc573777f40edf457a72c2881eaf75bb6720c1ef8484198e50c3031da' 
  AND token = 'V3rsDf7tRqGNthQHmUDm08/z7y6jDOPPB8qTzVaLpmM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}