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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7faa7d761fed929ed9883663185d24acd5e6bcb7ae4199b100728b71d65d9a57' 
  AND token = '5d43icQiJQrkd4NkDWLGEpyXGqBrVGb1I+QEaMahYuk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}