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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9761cf07c48d3a3cb3f504909c7e65f9c937f7957d1a0b33d25490d5d3bb303a' 
  AND token = 'su2EZlAFp/zTQxhYHaQ4XbRofaXQekNmH5LdAS5UQ7o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}