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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a786b46de3a5dde3ba4b9b86401ff8fc73c6435fc971a0533ed09465ab22333' 
  AND token = 'Zkc8na/Az83IqYxwO5ZIFn/oMdupUvlA0UC5ze9wkVo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}