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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2da8cbd11d325be5749737af2f73372423bc4467b6dc201b21be738a03b9a9b7' 
  AND token = 'F7As5eu6hmGvhX04b4GUQJB1oXbUPwnIKnUB13mG3E4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}