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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c5b14726046da858882cf0e4d7c9cfc26e5b17c2ad38593fe5de3440f787af18' 
  AND token = 'AD+2bsaZWEKFhWXTIHMQXzJ3vRFqCK0ZZ8rov7j4O8s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}