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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '14c1c360b9175a79fbfb3e637f42c39a3e876830bea54c0def47e36d045453c6' 
  AND token = 'YbmOdWZN8jUbLE0VEhNzu1/1KhjixlB9WdqJ3dbL0uU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}