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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41bddfa42efec26837b58ff57fa95edca519acad0e9176d8295c19bc7948eb27' 
  AND token = 'ATW0UDLKbz+9c+Yzx/O4IBtTlZHnlHrWyBU0OvBhxs8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}