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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43b13330404fd9039492a52a3b18078cc7e639fb5e1ceac4cb4a9100396a7782' 
  AND token = 'FI3x6Ztt+5qLfjatogkSeUi0lzcPhBpUAADafhgQI0A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}