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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c2faadb08807af2ef28cb1f0ee43780129b864a7379a2bde4e012a685338230' 
  AND token = 'xTFQCsmySOI9NUEpcW12mYTd9PhItPuR4ZtXtc+egkM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}