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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '777bc100a703f59bb6c326f7fe0a647e90178d8b119dde14c352fef2d9137e71' 
  AND token = 'NsMIAyWsRGuX/tQXWWRbYeiNiTerZEmJH24c4WdNbns=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}