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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aaa1e33ff96529ded5c8329b2bf8a0e02027cfb6b35b41409a667eb221f57988' 
  AND token = 'I3nT7pDAKDE4qpyGG0mfYXZ8YnswdGFrTFeBU5s+R6Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}