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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ac7f5cd2322c04c28a0ab52cac1a1292eb3c17e2ea07be3e343326133107e9a9' 
  AND token = 'BONfuQoWcW+0+gAzT8NskUUIJXE0lgBh1mBUtC6RID0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}