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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22ffe425c165e38b93f3307b825329b090881133c7f50d0f9f5658233e595802' 
  AND token = 'G2QGGDL0oEj6EgsFozcO1eSv6c3FIRLGJDNZYh7qpeU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}